The Autoimmune Registry
Tolosa-Hunt syndrome Graphs for this disease are generated based on data from the Autoimmune Registry Inc.
For more information on our data sources, please visit here.
For help with understanding the disease profile tabs and charts, please visit here.
  • Names
    • Tolosa-Hunt syndrome
    • Non-specific inflammation of the cavernous sinus
    • Non-specific inflammation of the superior orbital fissure
    • Painful Ophthalmoplegia
    • Reflex sympathetic dystrophy
    Abbreviations: THS
    Category: Nervous System
    Prevalence 300 cases in the US (Iaconetta 2005). Female/Male ratio: 6.0x.
    Age of Onset No data.
    Description Patients with Tolosa-Hunt syndrome experience episodes of severe headaches surrounding the eyes, along with restricted eye movement that is painful (ophthalmoplegia). Normally, only one eye is affected and will frequently appear protruded. Symptoms may also include nerve abnormalities, such as eyelid drooping, double vision, large pupil, and numbness of the face. This disorder typically occurs in relapsing flares. The cause of Tolosa-Hunt syndrome is unknown but is associated with the inflammation within the eyes and may be autoimmune.

    Not confirmed as an autoimmune or autoinflammatory disease.
    Patient Groups
    Bloggers
      Symptoms
      Resources Link to Clinical Trials
      Link to PubMed
      References Link to Mayo Clinic
      Link to Cleveland Clinic
      Link to Healthline
      Profile by: Autoimmune Registry
    • Profile updated September 2024
    • Charts generated Oct 12, 2024 at 12:54 PM ET
      		•

      Tolosa-Hunt syndrome sex breakdown


      Tolosa-Hunt syndrome age breakdown

      Join the registry!

      Graphs for this disease are generated based on data from the Autoimmune Registry Inc.

    • Tolosa-Hunt syndrome top autoimmune comorbidities


      Join the registry!

      * Disease is suspected as autoimmune, but unconfirmed.
      Data Source: Graphs on this page represent data from the Autoimmune Registry Inc. here. To protect participant anonymity, results derived from fewer than 5 participants are not graphed. The Autoimmune Registry Inc is a 501(c)(3) non-profit supported by donors like you.


    • Join the registry!

      * Biologic medications.
      Data Source: Graphs on this page represent data in electronic health records from the All of Us research database. As of July 2024, there are 451,000 sets of electronic health records collected from participants. A snapshot of the data can be found here. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
      The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.

    • Quick links: 
      Quick Links

      Join the registry!

      Data Source: Graphs on this page represent data in self-reported survey results from the All of Us research database. As of July 2024, there are 560,000 participants who have completed these surveys. This dataset, however, may not be representative of the US population. A snapshot of the data can be found here. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
      The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.

    • Quick links: 
      Quick Links

      Join the registry!

      Graphs for this disease are generated based on data from the Autoimmune Registry Inc.