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Mooren's ulcer Insufficent data to report on this disease.
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  • Names
    • Mooren's ulcer
    • Corneal Ulcer
    • Peripheral Ulcerative Keratitis

    Category: Nervous System
    Prevalence Extremely rare. Fewer than 100 cases in the US. No studies found. Female/Male ratio: Unknown.
    Age of Onset Onset typically occurs at age 48.
    Description Mooren's Ulcer is a chronic eye condition that causes inflammation where the eye's covering (cornea) joins with the white part of the eye (sclera). This type of inflammation is called Peripheral Ulcerative Keratitis (PUK). These persistent peripheral ulcers of the cornea often spread into and around the eye. There are several variants of this disorder: Aggressive Bilateral Mooren's Ulcers patients usually have an ulcer in one eye and congestion or discharge in the other eye. Pain is milder, and grey patches may develop within 2 mm of the border between the cornea and the white of the eye (limbus). Bilateral Indolent Mooren's Ulcers affect both eyes, with one eye typically showing more severity. Discomfort may occur with minimal inflammation. Unilateral Mooren's ulcers can occur in one or both eyes and is excessively painful. Redness and congestion are apparent, but inflammation is seen within 3 mm of the limbus. Mooren's Ulcer is believed to be an autoimmune disorder, but more research is needed. The condition can be benign, with few symptoms and low risk of complications, or malignant, with severe symptoms. Without medical care, malignant cases may lead to vision loss, but treatments are available to prevent this.

    Not confirmed as an autoimmune or autoinflammatory disease.
    ICD-10 Code: H16.05     SNOMED Code: 22440001
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      Symptoms
      Resources Link to Clinical Trials
      Link to PubMed
      References Link to Mayo Clinic
      Link to Cleveland Clinic
      Link to Healthline
      Profile by: Katelynn Hunter
    • Profile updated September 2024
    • Charts generated Oct 12, 2024 at 12:54 PM ET
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    • Mooren's ulcer top comorbidities/symptoms
      Chart is omitted due to low report count.


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      * Disease is suspected as autoimmune, but unconfirmed.
      Data Source: Graphs on this page represent data from the Autoimmune Registry Inc. here. To protect participant anonymity, results derived from fewer than 5 participants are not graphed. The Autoimmune Registry Inc is a 501(c)(3) non-profit supported by donors like you.

    • Anti-inflammatory / specialty medications and supplements

      Mooren's ulcer top immunosuppressants / autoimmune therapies


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      * Biologic medications.
      Data Source: Graphs on this page represent data in electronic health records from the All of Us research database. As of July 2024, there are 451,000 sets of electronic health records collected from participants. A snapshot of the data can be found here. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
      The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.

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      Patient-reported 7-day average pain
      Chart is omitted due to low report count.


      Patient-reported 7-day average fatigue
      Chart is omitted due to low report count.


      General physical health
      Chart is omitted due to low report count.


      General mental health
      Chart is omitted due to low report count.


      Social and relationship satisfaction
      Chart is omitted due to low report count.


      General quality of life
      Chart is omitted due to low report count.


      Ability to carry out social roles and activities
      Chart is omitted due to low report count.


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      Data Source: Graphs on this page represent data in self-reported survey results from the All of Us research database. As of July 2024, there are 560,000 participants who have completed these surveys. This dataset, however, may not be representative of the US population. A snapshot of the data can be found here. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
      The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.

    • Quick links: 
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      Concerns about ability to pay
      Chart is omitted due to low report count.


      Feeling unheard by healthcare providers
      Chart is omitted due to low report count.


      Patient employment status
      Chart is omitted due to low report count.


      Patient insurance coverage
      Chart is omitted due to low report count.


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      Insufficent data to report on this disease.