The Autoimmune Registry
Acute disseminated encephalomyelitis Graphs for this disease are generated based on data from the Autoimmune Registry Inc.
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  • Names
    • Acute disseminated encephalomyelitis
    • Acute hemorrhagic leukoencephalitis (subtype)
    • Hurst's disease
    • Nonvasculitic autoimmune inflammatory meningoencephalitis
    • Weston-Hurst syndrome
    Abbreviations: ADEM
    Category: Nervous System
    Incidence From 233 to 1,999 cases in the US per year (Filippi and Rocca 2020). Female/Male ratio: 4.5x.
    Age of Onset Onset typically between 5 and 10 years old for children and between 30 and 40 years old for adults.
    Description Acute disseminated encephalomyelitis (ADEM) is caused when inflammation stemming from fever or immunization damages the myelin sheaths of nerves in the brain, spinal cord, and occasionally the optic nerves, leading to abnormal nerve function. Onset is brief but intense and occurs predominantly in children. Patients often experience complete recovery within 6 months and do not experience relapses. The risk of developing ADEM depends on several factors, including genetics, exposure to infectious organisms, immunization exposure, and lighter skin pigmentation. ADEM can affect people of all ethnic backgrounds globally. Between 50% to 85% of ADEM cases are linked to a prior infection or vaccination, with many following a viral or bacterial infection. Nonetheless, the specific pathogen causing ADEM is often unknown.

    Evidence of autoimmunity: Antibody
    ICD-10 Code: G36.1     SNOMED Code: 72986009
    Patient Groups
    Bloggers
    Symptoms
    Resources Link to Clinical Trials
    Link to PubMed
    References Link to Mayo Clinic
    Link to Cleveland Clinic
    Link to Healthline
    Profile by: Nethra Giri
  • Profile updated March 2024
  • Charts generated Oct 12, 2024 at 12:54 PM ET
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    Acute disseminated encephalomyelitis sex breakdown


    Acute disseminated encephalomyelitis age breakdown

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    Graphs for this disease are generated based on data from the Autoimmune Registry Inc.

  • Acute disseminated encephalomyelitis top comorbidities/symptoms
    Chart is omitted due to low report count.

    Acute disseminated encephalomyelitis top autoimmune comorbidities


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    * Disease is suspected as autoimmune, but unconfirmed.
    Data Source: Graphs on this page represent data from the Autoimmune Registry Inc. here. To protect participant anonymity, results derived from fewer than 5 participants are not graphed. The Autoimmune Registry Inc is a 501(c)(3) non-profit supported by donors like you.

  • Anti-inflammatory / specialty medications and supplements

    Acute disseminated encephalomyelitis top immunosuppressants / autoimmune therapies


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    * Biologic medications.
    Data Source: Graphs on this page represent data in electronic health records from the All of Us research database. As of July 2024, there are 451,000 sets of electronic health records collected from participants. A snapshot of the data can be found here. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
    The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.

  • Quick links: 
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    Patient-reported 7-day average pain
    Chart is omitted due to low report count.


    Patient-reported 7-day average fatigue
    Chart is omitted due to low report count.


    General physical health
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    General mental health
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    Social and relationship satisfaction
    Chart is omitted due to low report count.


    General quality of life
    Chart is omitted due to low report count.


    Ability to carry out social roles and activities
    Chart is omitted due to low report count.


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    Data Source: Graphs on this page represent data in self-reported survey results from the All of Us research database. As of July 2024, there are 560,000 participants who have completed these surveys. This dataset, however, may not be representative of the US population. A snapshot of the data can be found here. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
    The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.

  • Quick links: 
    Quick Links

    Patient employment status
    Chart is omitted due to low report count.


    Patient insurance coverage
    Chart is omitted due to low report count.


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    Graphs for this disease are generated based on data from the Autoimmune Registry Inc.