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Rheumatic Chorea
Graphs for this disease are generated based on data from the Autoimmune Registry Inc.
For more information on our data sources, please visit
here
.
For help with understanding the disease profile tabs and charts, please visit
here
.
Disease Profile
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Names
Rheumatic Chorea
St. Vitus Dance
Sydenham chorea
Syndenham chorea
Category:
Musculoskeletal
Prevalence
Published: Extremely rare. Fewer than 100 cases in the US. No studies found.
ARI Data:
An estimated 1,072 cases in the U.S. Female/Male ratio: 1.3x.
Age of Onset
Onset typically occurs between ages 5 and 15.
Description
Rheumatic chorea, also called Sydenham chorea, is a rare neurological disorder typically occurring during childhood. It is caused by an autoimmune reaction following infection from the same bacterium that causes rheumatic fever. It leads to chorea: sudden, continuous, involuntary movements affecting the entire body. Symptoms can last in children anywhere from 3 weeks to several months. Patients with mild cases recover on their own in a few weeks, but treatment is available to provide relief to those with severe symptoms.
Since antibiotics have reduced the incidence of rheumatic fever, the incidence of rheumatic chorea in developed countries like the US is much lower than in developing countries. (Note that we could not find a study that supports a statistic cited in several papers that 30% of patients with rheumatic fever develop rheumatic chorea).
Not confirmed as an autoimmune or autoinflammatory disease.
ICD-10 Code:
I02
     SNOMED Code:
46826000
Patient Groups
Sydenham’s Chorea Association (Non-profit)
Child Neurology Foundation (Non-profit)
Brain Foundation (Non-profit)
Bloggers
Click here to tell us about a blogger that writes about Rheumatic Chorea.
Symptoms
Unsteady gait
Obsessions
Mood changes
Compulsive behavior
Involuntary movements
Anxiety
Difficulty speaking
Confusion
Weakness
Irritability
Difficulty concentrating
Difficulty walking
Resources
Link to Clinical Trials
Link to PubMed
References
Link to Cleveland Clinic
Profile by:
Hannah Link
Profile updated February 2025
Charts generated Feb 19, 2025 at 06:51 PM ET
Rheumatic Chorea sex breakdown
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Rheumatic Chorea sex breakdown
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Rheumatic Chorea age breakdown
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Rheumatic Chorea age breakdown
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Graphs for this disease are generated based on data from the Autoimmune Registry Inc.
Rheumatic Chorea top autoimmune comorbidities
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Rheumatic Chorea top autoimmune comorbidities
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* Disease is suspected as autoimmune, but unconfirmed.
Data Source:
Graphs on this page represent data from the Autoimmune Registry Inc.
here
. To protect participant anonymity, results derived from fewer than 5 participants are not graphed. The Autoimmune Registry Inc is a 501(c)(3) non-profit supported by donors like you.
Join the registry!
* Biologic medications.
Data Source:
Graphs on this page represent data in electronic health records from the All of Us research database. As of July 2024, there are 451,000 sets of electronic health records collected from participants. A snapshot of the data can be found
here
. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.
Quick links:
Quick Links
Join the registry!
Data Source:
Graphs on this page represent data in self-reported survey results from the All of Us research database. As of July 2024, there are 560,000 participants who have completed these surveys. This dataset, however, may not be representative of the US population. A snapshot of the data can be found
here
. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.
Quick links:
Quick Links
Join the registry!
Graphs for this disease are generated based on data from the Autoimmune Registry Inc.